CL-275838

Modify Date: 2024-04-05 18:37:36

CL-275838 Structure
CL-275838 structure
Common Name CL-275838
CAS Number 115931-65-2 Molecular Weight 506.52200
Density 1.33g/cm3 Boiling Point 636.7ºC at 760mmHg
Molecular Formula C27H25F3N6O Melting Point N/A
MSDS N/A Flash Point 338.9ºC

 Use of CL-275838


CL-275838 is a memory-enhancing agent, also with potent antidepressant activities.

 Names

Name 4-[2-(4-benzylpiperazin-1-yl)acetyl]-7-[3-(trifluoromethyl)phenyl]-5H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Synonym More Synonyms

 CL-275838 Biological Activity

Description CL-275838 is a memory-enhancing agent, also with potent antidepressant activities.
Related Catalog
In Vivo CL 275,838 metabolism has sex-dependent differences in rat. CL 275,838 does not appreciably affect its own oxidation or cause significant hepatic microsomal enzyme induction in the male or female rat, except for slight enhancement of some components of the P450 system at doses (300 mg/kg once daily for 7 days) well above the effective pharmacological range[1].
References

[1]. Ferrarese A, et al. Hepatic microsomal metabolism of the potential memory-enhancing agent, CL 275,838, to its desbenzyl derivative. Xenobiotica. 1993 Sep;23(9):1007-16.

 Chemical & Physical Properties

Density 1.33g/cm3
Boiling Point 636.7ºC at 760mmHg
Molecular Formula C27H25F3N6O
Molecular Weight 506.52200
Flash Point 338.9ºC
Exact Mass 506.20400
PSA 68.40000
LogP 3.76798
Vapour Pressure 4.11E-16mmHg at 25°C
Index of Refraction 1.634
Storage condition 2-8℃

 Synonyms

CL-275838