Xenin-8 TFA

Modify Date: 2024-04-05 21:50:01

Xenin-8 TFA structure	Common Name	Xenin-8 TFA
	CAS Number	117442-28-1	Molecular Weight	1046.27000
	Density	1.43±0.1 g/cm3(Predicted)	Boiling Point	N/A
	Molecular Formula	C₅₁H₇₉N₁₅O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Xenin-8 TFA

Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1].

Name	Xenin 8
Synonym	More Synonyms

Description	Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Xenin-8 augments Arginine-induced insulin release (by 40%) and potentiates the glucagon responses to both Arginine (by 60%), Carbachol (by 50%). Xenin-8 counteracts the inhibition of glucagon release induced by increasing the glucose concentration[1].
References	[1]. Ramona A Silvestre, et al. Stimulatory effect of xenin-8 on insulin and glucagon secretion in the perfused rat pancreas. Regul Pept. 2003 Aug 15;115(1):25-9.