Argipressin Acetate

Modify Date: 2025-08-27 20:51:41

Argipressin Acetate structure	Common Name	Argipressin Acetate
	CAS Number	129979-57-3	Molecular Weight	1144.28000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₈H₆₉N₁₅O₁₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Argipressin Acetate

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4].

Name	<8-arginine>vasopressin
Synonym	More Synonyms

Description	Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor Research Areas >> Neurological Disease
In Vitro	Argipressin (Arg8-vasopressin) (acetate) 在啮齿动物和人类 β 细胞中诱导增殖并阻止细胞因子诱导的细胞凋亡[1]。 Cell Proliferation Assay[1] Cell Line: clonal BRIN BD11 and 1.1B4 cells Concentration: 10-6 M Incubation Time: 2 h Result: Increased proliferation of rodent and human beta-cells. Apoptosis Analysis[1] Cell Line: clonal BRIN BD11 and 1.1B4 cells Concentration: 10-6 M Incubation Time: 2 h Result: Protected against cytokine-induced beta-cell apoptosis.
In Vivo	Argipressin (diacetate) (AVP (diacetate)) (25 nmol/kg bw; 腹腔内注射; 一次) 显着降低小鼠的总体 AUC 葡萄糖值，但不增加小鼠的胰岛素水平[1]。 Animal Model: NIH Swiss mice (adult; male; 12-14weeks)[1] Dosage: 25 nmol/kg bw Administration: AVP (25 nmol/kg bw; intraperitoneal injection; once) Result: Reduced (P<0.001) overall AUC glucose values，but not increased insulin levels in mice.
References	[1]. Shruti Mohan, et al. Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival. Biochimie. [2]. Thibonnier M, et al. Multiple signaling pathways of V1-vascular vasopressin receptors of A7r5 cells. Endocrinology. 1991 Dec;129(6):2845-56. [3]. Moriya T, et al. Vasopressin-induced intracellular Ca²⁺ concentration responses in non-neuronal cells of the rat dorsal root ganglion. Brain Res. 2012 Nov 5;1483:1-12. [4]. Keun Suk Park, et al. Role of vasopressin in current anesthetic practice. Korean J Anesthesiol. 2017 Jun; 70(3): 245–257.

Molecular Formula	C₄₈H₆₉N₁₅O₁₄S₂
Molecular Weight	1144.28000
Exact Mass	1143.46000
PSA	549.33000
LogP	1.25190
Storage condition	2-8°C

Hazard Codes	Xn
Risk Phrases	20
Safety Phrases	36
WGK Germany	3

[ARG8]VASOPRESSIN TFA

ARGIPRESSIN ACETATE

[Arg8]Vasopressin acetate

ArgipressinAcetate

Argipressin Acetate

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Argipressin Acetate
Price: Check
Purity: 98.0%
Delivery: 10 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ARGIPRESSIN ACETATE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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