Enterostatin human

Modify Date: 2024-01-02 11:22:11

Enterostatin human structure	Common Name	Enterostatin human
	CAS Number	117830-79-2	Molecular Weight	496.56100
	Density	1.54g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₁H₃₆N₈O₆	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Enterostatin human

Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.

Name	(2S)-2-[[(2S)-1-[2-[[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Synonym	More Synonyms

Description	Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.
Related Catalog	Peptides Research Areas >> Metabolic Disease Natural Products >> Others
Target	Human Endogenous Metabolite
In Vitro	In the perfused ratpancreas, Enterostatin, at 100 mM, inhibits the insulin response to 9 mM glucose (by 70%), 0.1 mM tolbutamide (by 40%), and 5 mM arginine (by 70%)[1].
In Vivo	Chronically, enterostatin reduces fat intake, bodyweight, and body fat. This response may involve multiple metabolic effects of enterostatin, which include a reduction of insulin secretion, an increase in sympathetic drive to brown adipose tissue, and the stimulation of adrenal corticosteroid secretion[2]. Enterostatin enhances memory consolidation after central or oral administration at a dose of 10 nmol/mouse or 300 mg/kg, respectively, in a step-through type passive avoidance test in mice[3]. A dose of 38 nmol of enterostatin gives a significant inhibition of high-fat food intake, while at a higher dose of 76 nmol the inhibiting effect is lost. During the first hour, after injection of enterostatin, there is even a slight increase in food intake[4].
References	[1]. Silvestre RA, et al. Effect of enterostatin on insulin, glucagon, and somatostatin secretion in the perfused rat pancreas. Diabetes. 1996 Sep;45(9):1157-60. [2]. Erlanson-Albertsson C, et al. Enterostatin--a peptide regulating fat intake. Obes Res. 1997 Jul;5(4):360-72. [3]. Ohinata K, et al. Enterostatin (APGPR) enhances memory consolidation in mice. Peptides. 2007 Mar;28(3):719-21. [4]. Sörhede M, et al. Enterostatin: a gut-brain peptide regulating fat intake in rat. J Physiol Paris. 1993;87(4):273-5.

Density	1.54g/cm3
Molecular Formula	C₂₁H₃₆N₈O₆
Molecular Weight	496.56100
Exact Mass	496.27600
PSA	224.04000
Index of Refraction	1.681
Storage condition	-20°C

Hazard Codes	Xi

CLAP

H-Ala-Pro-Gly-Pro-Arg-OH

Enterostatin human

APGPR

APGPR Enterostatin

Ala-pro-gly-pro-arg

Procolipase activation peptide

ALA-PRO-GLY-PRO-ARG

Enterostatin, human, mouse, rat

GL Biochem (Shanghai) Ltd.
China
Product Name: Enterostatin
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Enterostatin human
Price: ￥938.0/5mg ￥3728.0/25mg
Purity: 97.0%
Stocking Period: 1 Day
Contact: Liu jia

Zhejiang Hangyu API Co., Ltd
China
Product Name: Enterostatin
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

Get all suppliers and price by the below link:

Enterostatin human suppliers

Price: ￥880/1 mg

Reference only. check more Enterostatin human price

Enterostatin human

Use of Enterostatin human

Names

Enterostatin human Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms