Stiripentol-d9
Modify Date: 2024-01-10 17:45:22
Stiripentol-d9 structure
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Common Name | Stiripentol-d9 | ||
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| CAS Number | 1185239-64-8 | Molecular Weight | 243.34600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H9D9O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Stiripentol-d9Stiripentol-d9 (BCX2600-d9) is the deuterium labeled Stiripentol. Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediatated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59±0.07 and 0.516±0.065 μM and IC50 of 1.58 and 3.29 μM, respectively[1][2]. |
| Name | (1E)-1-(1,3-Benzodioxol-5-yl)-4,4-bis[(2H3)methyl](5,5,5-2H3)-1-penten-3-ol |
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| Synonym | More Synonyms |
| Description | Stiripentol-d9 (BCX2600-d9) is the deuterium labeled Stiripentol. Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediatated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59±0.07 and 0.516±0.065 μM and IC50 of 1.58 and 3.29 μM, respectively[1][2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C14H9D9O3 |
|---|---|
| Molecular Weight | 243.34600 |
| Exact Mass | 243.18200 |
| PSA | 38.69000 |
| LogP | 2.83550 |
| Stiripentol-d9 |