IKK-16
Modify Date: 2024-01-13 18:44:11
IKK-16 structure
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Common Name | IKK-16 | ||
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| CAS Number | 1186195-62-9 | Molecular Weight | 520.09 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H30ClN5OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IKK-16IKK 16 hydrochloride is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively[1]. IKK16 also inhibits leucine-rich repeat kinase-2 (LRRK2) with an IC50 of 50 nM[2]. |
| Name | [4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone hydrochloride (1:1) |
|---|---|
| Synonym | More Synonyms |
| Description | IKK 16 hydrochloride is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively[1]. IKK16 also inhibits leucine-rich repeat kinase-2 (LRRK2) with an IC50 of 50 nM[2]. |
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| Related Catalog | |
| Target |
IKK2:40 nM (IC50) IKK1:200 nM (IC50) IKK:70 nM (IC50) LRRK2:50 nM (IC50) |
| References |
| Molecular Formula | C28H30ClN5OS |
|---|---|
| Molecular Weight | 520.09 |
| Exact Mass | 519.185974 |
| (4-{[4-(1-Benzothiophen-2-yl)pyrimidin-2-yl]amino}phenyl)[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone hydrochloride (1:1) |
| Methanone, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-, hydrochloride (1:1) |
| (4-{[4-(1-Benzothiophen-2-yl)-2-pyrimidinyl]amino}phenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]methanone hydrochloride (1:1) |
| IKK-16 |