Tizanidine-d4

Modify Date: 2024-01-04 18:31:40

Tizanidine-d4 structure	Common Name	Tizanidine-d4
	CAS Number	1188331-19-2	Molecular Weight	257.73600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₄ClD₄N₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tizanidine-d4

Tizanidine-d4 is the deuterium labeled Tizanidine. Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons[1][2].

Name	5-chloro-N-(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
Synonym	More Synonyms

Description	Tizanidine-d4 is the deuterium labeled Tizanidine. Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Curr Med Res Opin. 2008 Feb;24(2):425-39.

Molecular Formula	C₉H₄ClD₄N₅S
Molecular Weight	257.73600
Exact Mass	257.04400
PSA	90.44000
LogP	1.55320

Tizanidine-d4