Mitoxantrone-d8 structure
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Common Name | Mitoxantrone-d8 | ||
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CAS Number | 1189974-82-0 | Molecular Weight | 452.53000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C22H20D8N4O6 | Melting Point | 145 °C | |
MSDS | N/A | Flash Point | N/A |
Use of Mitoxantrone-d8Mitoxantrone-d8 (mitozantrone-d8) is the deuterium labeled Mitoxantrone. Mitoxantrone is a topoisomerase II inhibitor and also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM[1][2]. |
Name | Mitoxantrone-d8 |
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Synonym | More Synonyms |
Description | Mitoxantrone-d8 (mitozantrone-d8) is the deuterium labeled Mitoxantrone. Mitoxantrone is a topoisomerase II inhibitor and also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM[1][2]. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
Melting Point | 145 °C |
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Molecular Formula | C22H20D8N4O6 |
Molecular Weight | 452.53000 |
Exact Mass | 452.25100 |
PSA | 163.18000 |
LogP | 0.78860 |
Hazard Codes | Xi |
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1,4-dihydroxy-5,8-bis[2-[(1,1,2,2-tetradeuterio-2-hydroxyethyl)amino]ethylamino]anthracene-9,10-dione |