2-nitro-4-aminophenol

Modify Date: 2025-08-24 00:56:35

2-nitro-4-aminophenol structure	Common Name	2-nitro-4-aminophenol
	CAS Number	119-34-6	Molecular Weight	154.123
	Density	1.5±0.1 g/cm3	Boiling Point	334.5±27.0 °C at 760 mmHg
	Molecular Formula	C₆H₆N₂O₃	Melting Point	125-127 °C(lit.)
	MSDS	Chinese USA	Flash Point	156.1±23.7 °C
	Symbol	GHS07	Signal Word	Warning

Name	4-Amino-2-nitrophenol
Synonym	More Synonyms

Density	1.5±0.1 g/cm3
Boiling Point	334.5±27.0 °C at 760 mmHg
Melting Point	125-127 °C(lit.)
Molecular Formula	C₆H₆N₂O₃
Molecular Weight	154.123
Flash Point	156.1±23.7 °C
Exact Mass	154.037842
PSA	92.07000
LogP	0.64
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.689
InChIKey	WHODQVWERNSQEO-UHFFFAOYSA-N
SMILES	Nc1ccc(O)c([N+](=O)[O-])c1

2-nitro-4-aminophenol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SJ6303000

CHEMICAL NAME :: Phenol, 4-amino-2-nitro-

CAS REGISTRY NUMBER :: 119-34-6

BEILSTEIN REFERENCE NO. :: 1368435

LAST UPDATED :: 199701

DATA ITEMS CITED :: 23

MOLECULAR FORMULA :: C6-H6-N2-O3

MOLECULAR WEIGHT :: 154.14

WISWESSER LINE NOTATION :: ZR DQ CNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1470 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 302 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1470 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 108 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 7680 ug/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),37,1988 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,43,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,43,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1706 No. of Facilities: 1356 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 11981 (estimated) No. of Female Employees: 9309 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S22-S24/25-S37/39-S26
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	SJ6303000
Hazard Class	6.1
HS Code	2922299090

Precursor 10
CAS#:123-30-8 4-Aminophenol CAS#:51-28-5 2,4-Dinitrophenol CAS#:2871-01-4 2-[(4-Amino-2-n... CAS#:5307-14-2 2-Nitro-1,4-ben...
CAS#:364-76-1 4-Fluoro-3-nitr... CAS#:635-22-3 4-Chloro-3-nitr... CAS#:19077-69-1 2,4-dinitrosophenol CAS#:67329-17-3 2-nitro-4-(4'-s...
CAS#:51288-37-0 Acetamide,N-(4-... CAS#:51642-26-3 4-azido-2-nitro...
DownStream 6
CAS#:394-33-2 4-Fluoro-2-nitr... CAS#:577-72-0 4-Methoxy-3-nit... CAS#:103828-99-5 N-[[4-(5-iodopy... CAS#:21784-73-6 4-Iodo-2-nitrophenol
CAS#:51288-37-0 Acetamide,N-(4-... CAS#:51642-26-3 4-azido-2-nitro...

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Percutaneous absorption of nitroaromatic compounds: in vivo and in vitro studies in the human and monkey.

J. Invest. Dermatol. 84(3) , 180-3, (1985)

The percutaneous absorption of 2-nitro-p-phenylene-diamine, 4-amino-2-nitrophenol, nitrobenzene, p-nitroaniline, and 2,4-dinitrochlorobenzene was measured through human and monkey skin. Human studies ...

Plasma levels and kinetic disposition of 2,4-dinitrophenol and its metabolites 2-amino-4-nitrophenol and 4-amino-2-nitrophenol in the mouse.

J. Chromatogr. A. 344 , 177-86, (1985)

Eleven groups of six ICR mice were dosed orally with 22.5 mg/kg 2,4-dinitrophenol. Groups were sacrificed at 0, 0.5, 1, 2, 4, 6, 9, 12, 24, 48, and 96 h post-treatment and plasma was collected for ana...

The nonmutagenicity of purified 4-amino-2-nitrophenol in Salmonella typhimurium.

Carcinogenesis 3(7) , 809-13, (1982)

Two samples of 4-amino-2-nitrophenol were tested for mutagenicity in Salmonella typhimurium strains TA1535, TA1537, TA1538, TA98, and TA100. Significant mutagenic activity was detected with a sample o...

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Total 368, Current Page 1 of 37

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China
Product Name: 2-nitro-4-aminophenol
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Purity: 95.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Amino-2-nitrophenol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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2-nitro-4-aminophenol

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles3

2-nitro-4-aminophenolBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.