Vapendavir diphosphate

Modify Date: 2024-01-09 20:04:23

Vapendavir diphosphate Structure
Vapendavir diphosphate structure
Common Name Vapendavir diphosphate
CAS Number 1198151-75-5 Molecular Weight 578.45
Density N/A Boiling Point N/A
Molecular Formula C21H32N4O11P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Vapendavir diphosphate


Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

 Names

Name Vapendavir diphosphate

 Vapendavir diphosphate Biological Activity

Description Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].
Related Catalog
Target

EC50: 0.5-1.4 μM (EV71 strains)[1][2].

In Vitro Vapendavir (BTA798) efficiently inhibit the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C[2].
References

[1]. Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.

[2]. Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.

 Chemical & Physical Properties

Molecular Formula C21H32N4O11P2
Molecular Weight 578.45
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