SR-33805

Modify Date: 2024-01-06 17:13:11

SR-33805 Structure
SR-33805 structure
Common Name SR-33805
CAS Number 121346-32-5 Molecular Weight 654.77000
Density N/A Boiling Point 728.7ºC at 760 mmHg
Molecular Formula C34H42N2O9S Melting Point N/A
MSDS N/A Flash Point 394.5ºC

 Use of SR-33805


SR-33805 is a calcium channel antagonist potentially for the treatment of atherosclerosis and heart failure. SR-33805 restored the MI-altered cell shortening without affecting the Ca(2+) transient amplitude, suggesting an increase of myofilament Ca(2+) sensitivity in MI myocytes. A SR33805-induced sensitization of myofilament activation was found to be associated with a slight increase in myosin light chain-2 phosphorylation and a more significant decrease on troponin I (TnI) phosphorylation. Decreased TnI phosphorylation was related to inhibition of protein kinase A activity by SR-33805.

 Names

Name SR 33805 oxalate,3,4-Dimethoxy-N-methyl-N-[3-[4-[[1-methyl-3-(1-methylethyl)-1H-indol-2-yl]sulfonyl]phenoxy]propyl]benzeneethanamine

 Chemical & Physical Properties

Boiling Point 728.7ºC at 760 mmHg
Molecular Formula C34H42N2O9S
Molecular Weight 654.77000
Flash Point 394.5ºC
Exact Mass 654.26100
PSA 152.98000
LogP 6.33150
Vapour Pressure 4.34E-21mmHg at 25°C

 Safety Information

Hazard Codes Xi
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