HPK1-IN-8

Modify Date: 2025-10-26 19:17:09

HPK1-IN-8 Structure
HPK1-IN-8 structure
Common Name HPK1-IN-8
CAS Number 1214561-09-7 Molecular Weight 412.44
Density N/A Boiling Point N/A
Molecular Formula C19H17FN6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HPK1-IN-8


HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1.

 Names

Name HPK1-IN-8

 HPK1-IN-8 Biological Activity

Description HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1.
Related Catalog
References

[1]. Wang W, et al. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. 2021 Oct 19;60(41):3114-3124.

 Chemical & Physical Properties

Molecular Formula C19H17FN6O2S
Molecular Weight 412.44
InChIKey DKCQZXASVNYNLW-UHFFFAOYSA-N
SMILES Cc1nc2[nH]nc(C)n2c(=O)c1CC(=O)Nc1ncc(Cc2ccccc2F)s1
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