Indole-2-carboxylic acid-13C

Modify Date: 2024-01-12 19:11:53

Indole-2-carboxylic acid-13C Structure
Indole-2-carboxylic acid-13C structure
Common Name Indole-2-carboxylic acid-13C
CAS Number 1216839-31-4 Molecular Weight 162.15
Density N/A Boiling Point N/A
Molecular Formula C813CH7NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Indole-2-carboxylic acid-13C


Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].

 Names

Name Indole-2-carboxylic acid-13C

 Indole-2-carboxylic acid-13C Biological Activity

Description Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. 2-Indolecarboxylic acid.

[3]. J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3.

 Chemical & Physical Properties

Molecular Formula C813CH7NO2
Molecular Weight 162.15