1216839-31-4

1216839-31-4 structure

Name: Indole-2-carboxylic acid-13C
Chemical Name: Indole-2-carboxylic acid-13C
CAS Number: 1216839-31-4
Molecular Formula: C₈₁₃CH₇NO₂
Molecular Weight: 162.15
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2022-07-01 16:52:44
Modify Date: 2024-01-12 19:11:53
Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].

Name	Indole-2-carboxylic acid-13C

Description	Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. 2-Indolecarboxylic acid. [3]. J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3.

Molecular Formula	C₈₁₃CH₇NO₂
Molecular Weight	162.15