Milnacipran-d10 hydrochloride

Modify Date: 2024-01-30 15:44:19

Milnacipran-d10 hydrochloride Structure
Milnacipran-d10 hydrochloride structure
Common Name Milnacipran-d10 hydrochloride
CAS Number 1217774-40-7 Molecular Weight 292.87
Density N/A Boiling Point N/A
Molecular Formula C15H13D10ClN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Milnacipran-d10 hydrochloride


Milnacipran-d10 hydrochloride is the deuterium labeled Milnacipran hydrochloride. Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia[1][2].

 Names

Name Milnacipran-d10 hydrochloride

 Milnacipran-d10 hydrochloride Biological Activity

Description Milnacipran-d10 hydrochloride is the deuterium labeled Milnacipran hydrochloride. Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Moret C, et al. Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug. Neuropharmacology. 1985 Dec;24(12):1211-9.

[3]. Briley M, et al. Preclinical pharmacology of milnacipran. Int Clin Psychopharmacol. 1996 Sep;11 Suppl 4:9-14.

 Chemical & Physical Properties

Molecular Formula C15H13D10ClN2O
Molecular Weight 292.87