2-Iodoacetamide-d4

Modify Date: 2024-01-08 16:52:01

2-Iodoacetamide-d4 structure	Common Name	2-Iodoacetamide-d4
	CAS Number	1219802-64-8	Molecular Weight	188.99
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂D₄INO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-Iodoacetamide-d4

2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].

Name	IODOACETAMIDE-D4

Description	2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Peter G Hains, et al. The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification. J Proteome Resq. 2017 Sep 1;16(9):3443-3447. [3]. J J LALICH. Iodoacetamide induced gastric ulcers in rats. Proc Soc Exp Biol Med. 1962 Apr109:905-8.

Molecular Formula	C₂D₄INO
Molecular Weight	188.99