Biphenyl dimethyl dicarboxylate

Modify Date: 2026-07-17 01:08:27

Biphenyl dimethyl dicarboxylate Structure
Biphenyl dimethyl dicarboxylate structure
Common Name Biphenyl dimethyl dicarboxylate
CAS Number 792-74-5 Molecular Weight 270.280
Density 1.2±0.1 g/cm3 Boiling Point 407.0±38.0 °C at 760 mmHg
Molecular Formula C16H14O4 Melting Point 213-215 °C(lit.)
MSDS Chinese USA Flash Point 204.7±25.2 °C

 Use of Biphenyl dimethyl dicarboxylate


Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotectant obtained from Schizandra fructus and may induce a signal transduction similar to that associated with IFN[1].

 Names

Name Dimethyl biphenyl-4,4-dicarboxylate
Synonym More Synonyms

 Biphenyl dimethyl dicarboxylate Biological Activity

Description Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a hepatoprotectant obtained from Schizandra fructus and may induce a signal transduction similar to that associated with IFN[1].
Related Catalog
References

[1]. Joo SS, et al. Interferon signal transduction of biphenyl dimethyl dicarboxylate/amantadine and anti-HBV activity in HepG2 2.2.15. Arch Pharm Res. 2006 May;29(5):405-11.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 407.0±38.0 °C at 760 mmHg
Melting Point 213-215 °C(lit.)
Molecular Formula C16H14O4
Molecular Weight 270.280
Flash Point 204.7±25.2 °C
Exact Mass 270.089203
PSA 52.60000
LogP 3.71
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.559
InChIKey BKRIRZXWWALTPU-UHFFFAOYSA-N
SMILES COC(=O)c1ccc(-c2ccc(C(=O)OC)cc2)cc1

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2917399090

 Synthetic Route

 Customs

HS Code 2917399090
Summary 2917399090 aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles2

More Articles
Synthesis and properties of luminophores derived from fluorinated biphenyls. Ol'khovik VK, et al.

Russ. J. Org. Chem. 44(8) , 1172-79, (2008)

Dimethyl biphenyl-4, 4'-dicarboxylate. Ritzerfeld V, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 65(7) , 1677, (2009)

 Biphenyl dimethyl dicarboxylateBioassay

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Name: Hepatoprotective activity against concanavalin A induced C57BL/6 mouse livery injury ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5132300
Name: Hepatoprotective activity against concanavalin A induced C57BL/6 mouse livery injury ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5132302
Name: Hepatoprotective activity against concanavalin A induced C57BL/6 mouse livery injury ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5132296
Name: Hepatoprotective activity against concanavalin A induced C57BL/6 mouse livery injury ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5132298
Name: Hepatoprotective activity against concanavalin A induced C57BL/6 mouse livery injury ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5132292
Name: Hepatoprotective activity against concanavalin A induced C57BL/6 mouse livery injury ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5132294
Name: Hepatoprotective activity against concanavalin A induced livery injury in human HL770...
Source: ChEMBL
Target: L02
External Id: CHEMBL5132288
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: Hepatoprotective activity against concanavalin A induced C57BL/6 mouse livery injury ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5132290
Name: Hepatoprotective activity against concanavalin A induced livery injury in human HL770...
Source: ChEMBL
Target: L02
External Id: CHEMBL5132287
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 Synonyms

EINECS 212-341-4
MFCD00017201
Dimethyl (1,1'-biphenyl)-4,4'-dicarboxylate
Dimethyl biphenyl-4,4'-dicarboxylate
(1,1'-Biphenyl)-4,4'-dicarboxylic acid, dimethyl ester
Biphenyl dimethyl dicarboxylate
Dimethyl 4,4'-biphenyldicarboxylate
methyl 4-(4-methoxycarbonylphenyl)benzoate
[1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester
4,4'-Biphenyldicarboxylic acid, dimethyl ester
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