Phenoxyethanol

Modify Date: 2024-01-01 19:38:02

Phenoxyethanol structure	Common Name	Phenoxyethanol
	CAS Number	122-99-6	Molecular Weight	138.164
	Density	1.1±0.1 g/cm3	Boiling Point	245.2±0.0 °C at 760 mmHg
	Molecular Formula	C₈H₁₀O₂	Melting Point	11-13 °C
	MSDS	Chinese USA	Flash Point	105.3±14.1 °C
	Symbol	GHS07	Signal Word	Warning

Common Name	Phenoxyethanol
CAS Number	122-99-6	Molecular Weight	138.164
Density	1.1±0.1 g/cm3	Boiling Point	245.2±0.0 °C at 760 mmHg
Molecular Formula	C₈H₁₀O₂	Melting Point	11-13 °C
MSDS	Chinese USA	Flash Point	105.3±14.1 °C
Symbol	GHS07	Signal Word	Warning

Purity		Quantity		Budget		Inquiry

Use of Phenoxyethanol

Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[1].

Name	2-phenoxyethanol
Synonym	More Synonyms

Description	Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. B Dréno, et al. Safety Review of Phenoxyethanol When Used as a Preservative in Cosmetics. J Eur Acad Dermatol Venereol. 2019 Nov;33 Suppl 7:15-24.

Density	1.1±0.1 g/cm3
Boiling Point	245.2±0.0 °C at 760 mmHg
Melting Point	11-13 °C
Molecular Formula	C₈H₁₀O₂
Molecular Weight	138.164
Flash Point	105.3±14.1 °C
Exact Mass	138.068085
PSA	29.46000
LogP	1.16
Vapour density	4.8 (vs air)
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.526
Storage condition	room temp
Water Solubility	30 g/L (20 ºC)

Phenoxyethanol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM0350000

CHEMICAL NAME :: Ethanol, 2-phenoxy-

CAS REGISTRY NUMBER :: 122-99-6

BEILSTEIN REFERENCE NO. :: 1364011

LAST UPDATED :: 199710

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C8-H10-O2

MOLECULAR WEIGHT :: 138.18

WISWESSER LINE NOTATION :: Q2OR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1260 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14422 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 554 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 933 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 490 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 182 gm/kg/13W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17500 mg/kg/14D-I

TOXIC EFFECTS :: Gastrointestinal - alteration in gastric secretion Blood - other changes Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/m3/9W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Liver - liver function tests impaired

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 gm/kg/10D-I

TOXIC EFFECTS :: Behavioral - general anesthetic Kidney, Ureter, Bladder - other changes in urine composition Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 14 gm/kg/14D-I

TOXIC EFFECTS :: Blood - other changes Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 2000 ppm

REFERENCE :: MCBIA7 Microbios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- Volume(issue)/page/year: 28,7,1980 *** REVIEWS *** TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,747,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83449 No. of Facilities: 711 (estimated) No. of Industries: 18 No. of Occupations: 19 No. of Employees: 9560 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83449 No. of Facilities: 5523 (estimated) No. of Industries: 63 No. of Occupations: 77 No. of Employees: 111040 (estimated) No. of Female Employees: 46637 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	KM0350000
HS Code	29094990

溴原子

10097-32-2

溴酸钾

7758-01-2

Literature: Annalen der Physik (Weinheim, Germany), , vol. 138, p. 391 Annalen der Physik (Weinheim, Germany), , vol. 14, p. 487 Annalen der Physik (Weinheim, Germany), , vol. 52, p. 80

2(1H)-Pyrimidin...

7558-02-3

溴酸钾

7758-01-2

Literature: Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 29, p. 404 Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 46, p. 351 K: MVol.3, 1.6.1, page 578 - 579

氯酸钾

3811-04-9

溴酸钾

7758-01-2

Literature: Annalen der Physik (Weinheim, Germany), , vol. 138, p. 392

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HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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Phenoxytol

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EINECS 204-589-7

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2-Phenoxy-ethanol

Shanghai Nianxing Industrial Co., Ltd
China
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Phenoxyethanol
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DC Chemicals Limited
China
Product Name: Phenoxyethanol
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Phenoxyethanol
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Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Phenoxyethanol
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Purity: 99.0%
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HENAN NEWBLUE CHEMICAL CO.,LTD
China
Product Name: EPH / Ethylene glycol phenyl ether
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Purity: 99.0%
Delivery: 1 Day
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Email: info@newbluechem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Phenoxyethanol
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Phenoxyethanol suppliers

Price: ￥96/100g

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Phenoxyethanol

Use of Phenoxyethanol

Names

Phenoxyethanol Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

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Synonyms