Mivobulin

Modify Date: 2025-08-26 17:53:16

Mivobulin Structure
Mivobulin structure
Common Name Mivobulin
CAS Number 122332-18-7 Molecular Weight 315.40700
Density 1.36 Boiling Point 483ºC at 760mmHg
Molecular Formula C17H19N5O2 Melting Point N/A
MSDS N/A Flash Point 245.9ºC

 Use of Mivobulin


Mivobulin (NSC 613862) is a tubulin inhibitor, binds to tubulin in the region that overlaps the colchicine site, and inhibits tubulin polymerization. Mivobulin (NSC 613862) promotes the formation of abnormal polymers and a GTPase activity in the tubulin dimer. Anti-cancer activity[1].

 Names

Name ethyl N-[(2S)-5-amino-2-methyl-3-phenyl-1,2-dihydropyrido[3,4-b]pyrazin-7-yl]carbamate
Synonym More Synonyms

 Mivobulin Biological Activity

Description Mivobulin (NSC 613862) is a tubulin inhibitor, binds to tubulin in the region that overlaps the colchicine site, and inhibits tubulin polymerization. Mivobulin (NSC 613862) promotes the formation of abnormal polymers and a GTPase activity in the tubulin dimer. Anti-cancer activity[1].
Related Catalog
Target

Tubulin[1]

References

[1]. Barbier P, et al. The active GTP- and ground GDP-liganded states of tubulin are distinguished by the binding of chiral isomers of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate. Biochemistry. 1998 Jan 13;37(2):758-68.

 Chemical & Physical Properties

Density 1.36
Boiling Point 483ºC at 760mmHg
Molecular Formula C17H19N5O2
Molecular Weight 315.40700
Flash Point 245.9ºC
Exact Mass 315.18300
PSA 57.61000
LogP 2.90650
Vapour Pressure 1.74E-09mmHg at 25°C
Index of Refraction 1.671

 Safety Information

Hazard Codes Xi

 Synonyms

MIVOBULIN
mivobulin isethionate
UNII-96U5LG549X
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