Deriglidole

Modify Date: 2024-01-05 08:27:09

Deriglidole Structure
Deriglidole structure
Common Name Deriglidole
CAS Number 122830-14-2 Molecular Weight 255.35800
Density 1.27g/cm3 Boiling Point 456.4ºC at 760mmHg
Molecular Formula C16H21N3 Melting Point N/A
MSDS N/A Flash Point 229.8ºC

 Use of Deriglidole


Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors.

 Names

Name Deriglidole
Synonym More Synonyms

 Deriglidole Biological Activity

Description Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors.
Related Catalog
Target

Adrenoceptor[1]

In Vitro Deriglidole is a selective α2-receptor inhibitor. Deriglidole inhibits [3H]Clonidine and [3H]Idazoxan but not [3H]Prazosin binding to rat cortical and human platelet α2-adrenoceptors and is more selective than Idazoxan for peripheral receptors[1].
References

[1]. Natali A, et al. Effects of acute alpha 2-blockade on insulin action and secretion in humans. Am J Physiol. 1998 Jan;274(1 Pt 1):E57-64.

 Chemical & Physical Properties

Density 1.27g/cm3
Boiling Point 456.4ºC at 760mmHg
Molecular Formula C16H21N3
Molecular Weight 255.35800
Flash Point 229.8ºC
Exact Mass 255.17400
PSA 27.63000
LogP 1.97520
Vapour Pressure 1.62E-08mmHg at 25°C
Index of Refraction 1.686
Storage condition 2-8℃

 Synonyms

(+)-1,2,4,5-Tetrahydro-2-(2-imidazolin-2-yl)-2-propylpyrrolo(3,2,1-hi)indole
UNII-68EP8R4PMV
2-(4,5-dihydro-1h-imidazol-2-yl)-2-propyl-1,2,4,5-tetrahydropyrrolo[3,2,1-hi]indole