4-(MALEINIMIDO)PHENYL ISOCYANATE

Modify Date: 2024-01-07 12:24:57

4-(MALEINIMIDO)PHENYL ISOCYANATE Structure
4-(MALEINIMIDO)PHENYL ISOCYANATE structure
Common Name 4-(MALEINIMIDO)PHENYL ISOCYANATE
CAS Number 123457-83-0 Molecular Weight 214.177
Density 1.3±0.1 g/cm3 Boiling Point 375.4±25.0 °C at 760 mmHg
Molecular Formula C11H6N2O3 Melting Point 120-125ºC
MSDS Chinese USA Flash Point 180.8±23.2 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

 Names

Name N-(4-Isocyanatophenyl)maleimide PMPI
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 375.4±25.0 °C at 760 mmHg
Melting Point 120-125ºC
Molecular Formula C11H6N2O3
Molecular Weight 214.177
Flash Point 180.8±23.2 °C
Exact Mass 214.037842
PSA 66.81000
LogP 1.45
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.641
Storage condition 2-8°C

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H302-H312-H315-H317-H319-H332-H334-H335
Precautionary Statements P261-P280-P305 + P351 + P338-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn
Risk Phrases R20/21/22
Safety Phrases S22
RIDADR NONH for all modes of transport

 Synthetic Route

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4-(MALEINIMIDO)PHENYL ISOCYANATE Structure

4-(MALEINIMIDO)...

CAS#:123457-83-0

Literature: Lee, Kangwon; Ki, Chang Do; Kim, Hasuck; Chang, Ji Young Macromolecules, 2004 , vol. 37, # 15 p. 5544 - 5549

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4-(MALEINIMIDO)PHENYL ISOCYANATE Structure

4-(MALEINIMIDO)...

CAS#:123457-83-0

Literature: Gaina, Viorica; Gaina, Constantin Revue Roumaine de Chimie, 2003 , vol. 48, # 11 p. 881 - 890

~%

4-(MALEINIMIDO)PHENYL ISOCYANATE Structure

4-(MALEINIMIDO)...

CAS#:123457-83-0

Literature: Gaina, Viorica; Gaina, Constantin Revue Roumaine de Chimie, 2003 , vol. 48, # 11 p. 881 - 890

~%

4-(MALEINIMIDO)PHENYL ISOCYANATE Structure

4-(MALEINIMIDO)...

CAS#:123457-83-0

Literature: Gaina, Viorica; Gaina, Constantin Revue Roumaine de Chimie, 2003 , vol. 48, # 11 p. 881 - 890

 Articles4

More Articles
p-maleimidophenyl isocyanate: a novel heterobifunctional linker for hydroxyl to thiol coupling.

Bioconjug. Chem. 4 , 212, (1993)

p-Maleimidophenyl isocyanate (PMPI, 1) is a heterobifunctional cross-linking agent useful for thiol to hydroxyl coupling. Several maleimide-activated compounds were prepared and characterized and then...

Cys-93-betabeta-succinimidophenyl polyethylene glycol 2000 hemoglobin A. Intramolecular cross-bridging of hemoglobin outside the central cavity.

J. Biol. Chem. 275 , 5527, (2000)

Bis(maleidophenyl)-PEG2000 (Bis-Mal-PEG2000), a new bifunctional protein cross-linker targeted to sulfhydryl groups, introduces intra-tetrameric cross-links into oxy-HbA in nearly quantitative yields....

Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels.

Bioconjug. Chem. 18(3) , 874-85, (2007)

Hydrogels derived from synthetic polymers have been previously engineered to degrade under the activity of matrix metalloproteinases (MMPs). It is believed that these systems can act as extracellular-...

 Synonyms

4-(Maleinimido)phenyl isocyanate
1-(4-Isocyanatophenyl)-1H-pyrrole-2,5-dione
1-(4-isocyanatophenyl)pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-(4-isocyanatophenyl)-
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