4-(MALEINIMIDO)PHENYL ISOCYANATE
4-(MALEINIMIDO)PHENYL ISOCYANATE structure
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Common Name | 4-(MALEINIMIDO)PHENYL ISOCYANATE | ||
|---|---|---|---|---|
| CAS Number | 123457-83-0 | Molecular Weight | 214.177 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 375.4±25.0 °C at 760 mmHg | |
| Molecular Formula | C11H6N2O3 | Melting Point | 120-125ºC | |
| MSDS | Chinese USA | Flash Point | 180.8±23.2 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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p-maleimidophenyl isocyanate: a novel heterobifunctional linker for hydroxyl to thiol coupling.
Bioconjug. Chem. 4 , 212, (1993) p-Maleimidophenyl isocyanate (PMPI, 1) is a heterobifunctional cross-linking agent useful for thiol to hydroxyl coupling. Several maleimide-activated compounds were prepared and characterized and then shown to be reactive with thiol-containing proteins. Examp... |
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Cys-93-betabeta-succinimidophenyl polyethylene glycol 2000 hemoglobin A. Intramolecular cross-bridging of hemoglobin outside the central cavity.
J. Biol. Chem. 275 , 5527, (2000) Bis(maleidophenyl)-PEG2000 (Bis-Mal-PEG2000), a new bifunctional protein cross-linker targeted to sulfhydryl groups, introduces intra-tetrameric cross-links into oxy-HbA in nearly quantitative yields. Structural as well as crystallographic analyses of the cro... |
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Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels.
Bioconjug. Chem. 18(3) , 874-85, (2007) Hydrogels derived from synthetic polymers have been previously engineered to degrade under the activity of matrix metalloproteinases (MMPs). It is believed that these systems can act as extracellular-matrix (ECM) equivalents mimicking the degradation and remo... |
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Immobilization of oligonucleotides on poly(ethylene glycol) brush-coated Si surfaces.
Anal. Biochem. 311(1) , 27-32, (2002) High-density poly(ethylene glycol) (PEG) molecules are grafted onto Si surfaces in a brush-like configuration. We demonstrate that this surface is an excellent substrate for oligonucleotide immobilization. p-Maleimidophenyl isocyanate is used as a heterobifun... |