DS-5272
Modify Date: 2024-01-15 00:14:36
DS-5272 structure
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Common Name | DS-5272 | ||
|---|---|---|---|---|
| CAS Number | 1235575-97-9 | Molecular Weight | 703.675 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H38Cl2F2N6O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DS-5272A potent and orally active p53-MDM2 interaction inhibitor with IC50 of 2.4 nM; inhibits SJSA-1 cell proliferation with GI50 of 0.17 uM, demonstrates excellent antitumor efficacy on SJSA-1 xenografted models with high safety and good PK profiles. |
| Name | DS-5272 |
|---|
| Description | A potent and orally active p53-MDM2 interaction inhibitor with IC50 of 2.4 nM; inhibits SJSA-1 cell proliferation with GI50 of 0.17 uM, demonstrates excellent antitumor efficacy on SJSA-1 xenografted models with high safety and good PK profiles. |
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| References | References 1. Miyazaki M, et al. Bioorg Med Chem. 2015 May 15;23(10):2360-7. View Related Products by Target MDM2-p53 |
| Molecular Formula | C34H38Cl2F2N6O2S |
|---|---|
| Molecular Weight | 703.675 |