Fosifidancitinib
Modify Date: 2026-07-17 19:06:00
Fosifidancitinib structure
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Common Name | Fosifidancitinib | ||
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| CAS Number | 1237168-58-9 | Molecular Weight | 505.39 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 723.1±70.0 °C at 760 mmHg | |
| Molecular Formula | C21H21FN5O7P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 391.1±35.7 °C | |
Use of FosifidancitinibFosifidancitinib is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Fosifidancitinib is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 723.1±70.0 °C at 760 mmHg |
| Molecular Formula | C21H21FN5O7P |
| Molecular Weight | 505.39 |
| Flash Point | 391.1±35.7 °C |
| Exact Mass | 505.116272 |
| LogP | 2.15 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.680 |
| InChIKey | JTUBTEKGIDQZMZ-UHFFFAOYSA-N |
| SMILES | COc1cc(Nc2ncc(C)c(Nc3ccc4oc(=O)n(COP(=O)(O)O)c4c3)n2)cc(C)c1F |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the Chinese name of 1237168-58-9? |
| A: Chinese name of 1237168-58-9 is Fosifidancitinib. |
| Q: What are the uses of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: Main uses of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate: Fosifidancitinib is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases[1]. |
| Q: What is the InChIKey of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: InChIKey of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate is JTUBTEKGIDQZMZ-UHFFFAOYSA-N. |
| Q: What English synonyms does {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate have? |
| A: English synonyms of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate: {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate. |
| Q: What is the CAS number of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: CAS number of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate is 1237168-58-9. |
| Q: What is the SMILES notation of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: SMILES notation of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate is COc1cc(Nc2ncc(C)c(Nc3ccc4oc(=O)n(COP(=O)(O)O)c4c3)n2)cc(C)c1F. |
| Q: What is the English name of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: The English name of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate is {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate. |
| Q: What is the molecular formula of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: Molecular formula of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate is C21H21FN5O7P. |
| Q: What is the LogP of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: LogP of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate is 2.15. |
| Q: What is the boiling point of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate? |
| A: Boiling point of {5-[(Z)-{2-[(4-Fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4(3H)-pyrimidinylidene}amino]-2-oxo-1,3-benzoxazol-3(2H)-yl}methyl dihydrogen phosphate is 723.1±70.0 °C at 760 mmHg. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |