URAT1&XO inhibitor 2

Modify Date: 2024-01-24 16:22:55

URAT1&XO inhibitor 2 structure	Common Name	URAT1&XO inhibitor 2
	CAS Number	1239488-96-0	Molecular Weight	322.15
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₂BrNO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of URAT1&XO inhibitor 2

URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia[1].

Name	URAT1&XO inhibitor 2

Description	URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> URAT1 Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase
References	[1]. Hu Q, et al. (E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its dual inhibitory effects on XOD and URAT1. Biomed Pharmacother. 2017 Feb;86:88-94.

Molecular Formula	C₁₄H₁₂BrNO₃
Molecular Weight	322.15

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URAT1&XO inhibitor 2

Use of URAT1&XO inhibitor 2

Names

URAT1&XO inhibitor 2 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.