spermidine

Modify Date: 2026-08-02 15:26:00

spermidine structure	Common Name	spermidine
	CAS Number	124-20-9	Molecular Weight	145.246
	Density	0.9±0.1 g/cm3	Boiling Point	246.6±8.0 °C at 760 mmHg
	Molecular Formula	C₇H₁₉N₃	Melting Point	23-25 °C
	MSDS	Chinese USA	Flash Point	118.1±22.0 °C
	Symbol	GHS05	Signal Word	Danger

Use of spermidine

Spermidine, a precursor of spermine, is a polyamine derived from putrescine and could help stabilize some membranes and nucleic acid structures.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	spermidine
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Spermidine, a precursor of spermine, is a polyamine derived from putrescine and could help stabilize some membranes and nucleic acid structures.
Related Catalog	Research Areas >> Metabolic Disease Natural Products >> Others
Target	Human Endogenous Metabolite

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	0.9±0.1 g/cm3
Boiling Point	246.6±8.0 °C at 760 mmHg
Melting Point	23-25 °C
Molecular Formula	C₇H₁₉N₃
Molecular Weight	145.246
Flash Point	118.1±22.0 °C
Exact Mass	145.157898
PSA	64.07000
LogP	-0.84
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.475
InChIKey	ATHGHQPFGPMSJY-UHFFFAOYSA-N
SMILES	NCCCCNCCCN
Storage condition	2-8°C
Stability	Stable, but air-sensitive and very hygroscopic - store under argon. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
Water Solubility	H2O: 1 M at 20 °C, clear, colorless

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

spermidine MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EJ7000000

CHEMICAL NAME :: 1,4-Butanediamine, N-(3-aminopropyl)-

CAS REGISTRY NUMBER :: 124-20-9

BEILSTEIN REFERENCE NO. :: 1698591

LAST UPDATED :: 199706

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C7-H19-N3

MOLECULAR WEIGHT :: 145.29

WISWESSER LINE NOTATION :: Z4M3Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD30 - Lethal Dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD30 - Lethal Dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 9504 gm/kg/14D-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lung

DOSE/DURATION :: 200 mmol/L

REFERENCE :: IJRBA3 International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. (Taylor & Francis Inc., 242 Cherry St., Philadelphia, PA 19106) V.1- 1959- Volume(issue)/page/year: 9,185,1965

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive;
Risk Phrases	R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 2735 8/PG 2
WGK Germany	3
RTECS	EJ7000000
Packaging Group	III
Hazard Class	8
HS Code	2921290000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 8
CAS#:143565-69-9 4-aza-1,3-bis(1... CAS#:4748-73-6 3-(4-aminobutyl... CAS#:1111644-29-1 N-(3-benzylamin... CAS#:34450-15-2 N8-Acetylspermi...
CAS#:61345-84-4 N(1), N(12)-die... CAS#:64482-04-8 tetrahydroperip... CAS#:71-44-3 Spermine CAS#:25593-72-0 N-acetylspermine
DownStream 10
CAS#:182576-33-6 3,8,12,18-tetra... CAS#:71-44-3 Spermine CAS#:123-38-6 Propionaldehyde CAS#:109-76-2 1,3-Diaminopropane
CAS#:110-60-1 putrescine CAS#:352-92-1 3-aminopropanal CAS#:73453-98-2 4-(1,3-diazinan... CAS#:75956-68-2 4-[4-[(4-carbox...
CAS#:915404-83-0 2,3,4,6,7,8,9,1... CAS#:95245-09-3 2-phenyl-N-[4-[...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2921290000
Summary	2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

TYLCV-Is movement in planta does not require V2 protein.

Virology 477 , 56-60, (2015)

Tomato yellow leaf curl virus (TYLCV), a major tomato pathogen causing extensive crop losses, is a whitefly-transmitted geminivirus. V2 mutants of TYLCV-Is and related viruses tend to induce symptomle...

Hypoxia reduces MAX expression in endothelial cells by unproductive splicing.

FEBS Lett. 588(24) , 4784-90, (2014)

The MYC-MAX-MXD network is involved in the regulation of cell differentiation and proliferation. Hypoxia affects the expression levels of several members of this network, but changes specific to MAX e...

H4 histamine receptors inhibit steroidogenesis and proliferation in Leydig cells.

J. Endocrinol. 223(3) , 241-53, (2014)

The histamine H4 receptor (HRH4), discovered only 13 years ago, is considered a promising drug target for allergy, inflammation, autoimmune disorders and cancer, as reflected by a steadily growing num...

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

spermidine

N-(γ-aminopropyl)tetramethylenediamine

N-(3-Aminopropyl)butan-1,4-diamin

N'-(3-aminopropyl)butane-1,4-diamine

1,8-Diamino-4-azaoctane (N-(3-Aminopropyl)-1,4-diaminobutane

Additive Screening

N1-(3-Aminopropyl)butane-1,4-diamine

N-(3-Aminopropyl)-4-aminobutylamine

N-(3-Aminopropyl)butane-1,4-diamine

MFCD00008229

N-(3-Aminopropyl)-1,4-butanediamine

N-(g-Aminopropyl)tetramethylenediamine

EINECS 204-689-0

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the storage conditions for spermidine?

A: Storage conditions for spermidine: 2-8°C.

Q: What is the molecular formula of spermidine?

A: Molecular formula of spermidine is C7H19N3.

Q: What is the polar surface area (PSA) of spermidine?

A: Polar surface area (PSA) of spermidine is 64.07000.

Q: What are the upstream materials of spermidine?

A: Related upstream materials(CAS) of spermidine: 143565-69-9;4748-73-6;1111644-29-1;34450-15-2;61345-84-4;64482-04-8;71-44-3;25593-72-0.

Q: What are the uses of spermidine?

A: Main uses of spermidine: Spermidine, a precursor of spermine, is a polyamine derived from putrescine and could help stabilize some membranes and nucleic acid structures.

Q: What English synonyms does spermidine have?

A: English synonyms of spermidine: spermidine, N-(γ-aminopropyl)tetramethylenediamine, N-(3-Aminopropyl)butan-1,4-diamin, N'-(3-aminopropyl)butane-1,4-diamine, 1,8-Diamino-4-azaoctane (N-(3-Aminopropyl)-1,4-diaminobutane, Additive Screening, N1-(3-Aminopropyl)butane-1,4-diamine, N-(3-Aminopropyl)-4-aminobutylamine, N-(3-Aminopropyl)butane-1,4-diamine, MFCD00008229, N-(3-Aminopropyl)-1,4-butanediamine, N-(g-Aminopropyl)tetramethylenediamine, EINECS 204-689-0.

Q: What is the InChIKey of spermidine?

A: InChIKey of spermidine is ATHGHQPFGPMSJY-UHFFFAOYSA-N.

Q: What is the CAS number of spermidine?

A: CAS number of spermidine is 124-20-9.

Q: What is the SMILES notation of spermidine?

A: SMILES notation of spermidine is NCCCCNCCCN.

Q: What is the melting point of spermidine?

A: Melting point of spermidine is 23-25 °C.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Henan Tianfu Chemical Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: spermidine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: spermidine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: spermidine
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

Get all suppliers and price by the below link:

spermidine suppliers

Price: ￥605/10 mM * 1 mL in DMSO

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spermidine

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