Ganirelix

Modify Date: 2024-01-02 12:10:15

Ganirelix Structure
Ganirelix structure
 Common Name Ganirelix
CAS Number 124904-93-4 Molecular Weight 1570.32000
Density 1.31 g/cm3 Boiling Point N/A
Molecular Formula C80H113ClN18O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ganirelix


Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone relea[1].

 Names

Name ganirelix

 Ganirelix Biological Activity

Description Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone relea[1].
Related Catalog
In Vivo Ganirelix (0.1 mg/kg; s.c.; daily for 14 d) reduces luteinising hormone levels in female rats[2]. Animal Model: Female Sprague-Dawley rats, weighing 225–300 mg[2] Dosage: 0.1 mg/kg Administration: Subcutaneous injection, daily for 14 d Result: Reduced luteinising hormone levels.
References

[1]. Gillies PS, et al. Ganirelix. Drugs. 2000 Jan;59(1):107-11; discussion 112-3.

[2]. Russo A, et al. Effects of the gonadotropin-releasing hormone antagonist ganirelix on normal micturition and prostaglandin E(2)-induced detrusor overactivity in conscious female rats. Eur Urol. 2011 May;59(5):868-74.

 Chemical & Physical Properties

Density 1.31 g/cm3
Molecular Formula C80H113ClN18O13
Molecular Weight 1570.32000
Exact Mass 1568.84000
PSA 451.49000
LogP 7.99260
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Chemsrc provides Ganirelix(CAS#:124904-93-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Ganirelix are included as well.>> amp version: Ganirelix

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