Aza197

Modify Date: 2025-09-12 23:51:54

Aza197 Structure
Aza197 structure
Common Name Aza197
CAS Number 1249398-09-1 Molecular Weight 408.58
Density N/A Boiling Point N/A
Molecular Formula C24H36N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aza197


AZA197 is a selective small molecule inhibitor of Cdc42.AZA197 suppresses colon cancer cell proliferation, cell migration, invasion and increases apoptosis by down-regulating the PAK1 and ERK signaling pathways in vitro. AZA197 reduces tumor growth and significantly increases mouse survival in SW620 tumor xenografts[1].

 Names

Name AZA197

 Aza197 Biological Activity

Description AZA197 is a selective small molecule inhibitor of Cdc42.AZA197 suppresses colon cancer cell proliferation, cell migration, invasion and increases apoptosis by down-regulating the PAK1 and ERK signaling pathways in vitro. AZA197 reduces tumor growth and significantly increases mouse survival in SW620 tumor xenografts[1].
Related Catalog
References

[1]. Zins K, et al. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity. J Transl Med. 2013 Nov 27;11:295.  

 Chemical & Physical Properties

Molecular Formula C24H36N6
Molecular Weight 408.58
InChIKey SUXUDORZKKZLJK-UHFFFAOYSA-N
SMILES CCN(CC)CCCC(C)Nc1nc(C)cc(NCCc2c[nH]c3ccccc23)n1
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