Aza197

Modify Date: 2024-01-07 09:55:43

Aza197 structure	Common Name	Aza197
	CAS Number	1249398-09-1	Molecular Weight	408.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₆N₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Aza197

AZA197 is a selective small molecule inhibitor of Cdc42.AZA197 suppresses colon cancer cell proliferation, cell migration, invasion and increases apoptosis by down-regulating the PAK1 and ERK signaling pathways in vitro. AZA197 reduces tumor growth and significantly increases mouse survival in SW620 tumor xenografts[1].

Name	AZA197

Description	AZA197 is a selective small molecule inhibitor of Cdc42.AZA197 suppresses colon cancer cell proliferation, cell migration, invasion and increases apoptosis by down-regulating the PAK1 and ERK signaling pathways in vitro. AZA197 reduces tumor growth and significantly increases mouse survival in SW620 tumor xenografts[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> PAK Signaling Pathways >> GPCR/G Protein >> Ras Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Cell Cycle/DNA Damage >> PAK Signaling Pathways >> Stem Cell/Wnt >> ERK
References	[1]. Zins K, et al. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity. J Transl Med. 2013 Nov 27;11:295.

Molecular Formula	C₂₄H₃₆N₆
Molecular Weight	408.58

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Aza197
Price: Check
Purity: 100.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Aza197
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.