(S)-Bepotastine

Modify Date: 2024-01-03 21:29:52

(S)-Bepotastine Structure
(S)-Bepotastine structure
Common Name (S)-Bepotastine
CAS Number 125602-71-3 Molecular Weight 388.888
Density 1.3±0.1 g/cm3 Boiling Point 546.8±50.0 °C at 760 mmHg
Molecular Formula C21H25ClN2O3 Melting Point 56-58 °C
MSDS N/A Flash Point 284.5±30.1 °C

 Use of (S)-Bepotastine


Bepotastine is an orally active second-generation histamine H1 receptor antagonist. Bepotastine has the potential for allergic rhinitis and urticaria/pruritus treatment[1][2].

 Names

Name bepotastine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 546.8±50.0 °C at 760 mmHg
Melting Point 56-58 °C
Molecular Formula C21H25ClN2O3
Molecular Weight 388.888
Flash Point 284.5±30.1 °C
Exact Mass 388.155365
PSA 62.66000
LogP 3.67
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.605

 Safety Information

Hazard Codes Xn

 Synthetic Route

(S)-Bepotastine Structure

(S)-Bepotastine

CAS#:125602-71-3

~64%

(S)-Bepotastine Structure

(S)-Bepotastine

CAS#:125602-71-3

Literature: Ha, Tae Hee; Suh, Kwee-Hyun; Lee, Gwan Sun Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 2 p. 549 - 552
(S)-Bepotastine Structure

(S)-Bepotastine

CAS#:125602-71-3

~68%

(S)-Bepotastine Structure

(S)-Bepotastine

CAS#:125602-71-3

Literature: Hanmi Pharm. Co., Ltd. Patent: US2010/137367 A1, 2010 ; Location in patent: Page/Page column 3 ;

~%

(S)-Bepotastine Structure

(S)-Bepotastine

CAS#:125602-71-3

Literature: US2014/46068 A1, ;

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(S)-Bepotastine Structure

(S)-Bepotastine

CAS#:125602-71-3

Literature: US2014/46068 A1, ;

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(S)-Bepotastine Structure

(S)-Bepotastine

CAS#:125602-71-3

Literature: US2014/46068 A1, ;

 Synonyms

(+)-(S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid monobenzenesulfonate
4-[(S)-(4-chlorophenyl)-2-pyridinylMethoxy]
4-{4-[(S)-(4-Chlorophenyl)(2-pyridinyl)methoxy]-1-piperidinyl}butanoic acid
(+)-(S)-4-{4[(4-chlorphenyl)(2-pyridil)methoxy]piperidino}butyric acid monobenzenesulfonate
1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-
1-Piperidinebutanoic acid,4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]
4-[4-[(4-Chlorophenyl)pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid
(+)-(S)-4-[4-[1-(4-chlorophenyl)-1-(2-pyridyl)methoxy]piperidin-1-yl]butyric acid
[14C]-Bepotastine besilate
Bepotastine
4-(4-[(1S)(4-CHLOROPHENYL)-2-PYRIDYLMETHOXY]PIPERIDYL)BUTANOIC ACID
betotastine besilate
4-(4-((S)-(4-Chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic Acid
(+)-4-(((S)-p-Chloro-2-pyridylbenzyl)oxy)-1-piperidinebutyric Acid
betotastine
Bepreve
4-{4-[(S)-(4-Chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-yl}butanoic acid