2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol

Modify Date: 2024-01-31 10:46:08

2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol Structure
2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol structure
Common Name 2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol
CAS Number 125722-16-9 Molecular Weight 242.28800
Density N/A Boiling Point N/A
Molecular Formula C16H15FO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol


Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC50 of 2.48 μM for inhibition of calcium ionophore-induced LTB4 generation[1].

 Names

Name 4-[2-(4-fluorophenyl)ethenyl]-2,6-dimethylphenol
Synonym More Synonyms

  Biological Activity

Description Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC50 of 2.48 μM for inhibition of calcium ionophore-induced LTB4 generation[1].
Related Catalog
Target

IC50: 2.48 μM (LTB4)[1].

References

[1]. T C Noonan, et al. Effect of BI-L-239, A-64077 and MK-886 on leukotriene B4 synthesis by chopped guinea pig lung and on antigen-induced tracheal contraction in vitro. Prostaglandins. 1992 Dec;44(6):543-54.  

 Chemical & Physical Properties

Molecular Formula C16H15FO
Molecular Weight 242.28800
Exact Mass 242.11100
PSA 20.23000
LogP 4.31850
Vapour Pressure 1.79E-05mmHg at 25°C

 Synonyms

2,6-Dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol