4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile

Modify Date: 2025-08-22 20:04:56

4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile Structure
4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile structure
Common Name 4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile
CAS Number 125743-63-7 Molecular Weight 215.294
Density 1.1±0.1 g/cm3 Boiling Point 342.5±32.0 °C at 760 mmHg
Molecular Formula C13H17N3 Melting Point 69ºC
MSDS N/A Flash Point 144.5±14.4 °C

 Names

Name 4-(4-Methylpiperazinomethyl)benzonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 342.5±32.0 °C at 760 mmHg
Melting Point 69ºC
Molecular Formula C13H17N3
Molecular Weight 215.294
Flash Point 144.5±14.4 °C
Exact Mass 215.142242
PSA 30.27000
LogP 0.36
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.587
Storage condition 2-8℃

 Safety Information

Hazard Codes C
Risk Phrases 20/21/22-34
Safety Phrases 23-26-36/37/39-45
HS Code 2933599090

 Synthetic Route

~97%

4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile Structure

4-[(4-Methyl-1-...

CAS#:125743-63-7

Literature: NATCO PHARMA LIMITED; KOMPELLA, Amala Kishan; RACHAKONDA, Sreenivas; GAMPA, Venu Gopala Krishna; ADIBHATLA, Kali Satya Bhujanga Rao; NANNAPANENI, Venkaiah Chowdary Patent: WO2013/35102 A1, 2013 ; Location in patent: Page/Page column 20 ;

~66%

4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile Structure

4-[(4-Methyl-1-...

CAS#:125743-63-7

Literature: SMITHKLINE BEECHAM CORPORATION Patent: WO2004/9602 A1, 2004 ; Location in patent: Page 67-68 ; WO 2004/009602 A1

~92%

4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile Structure

4-[(4-Methyl-1-...

CAS#:125743-63-7

Literature: Liu, Haiyan; Xia, Wenpin; Luo, Yu; Lu, Wei Monatshefte fur Chemie, 2010 , vol. 141, # 8 p. 907 - 911

~%

4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile Structure

4-[(4-Methyl-1-...

CAS#:125743-63-7

Literature: Organic Process Research and Development, , vol. 16, # 11 p. 1794 - 1804

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-[(4-Methyl-1-piperazinyl)methyl]benzonitrile
4-[(4-Methylpiperazin-1-yl)methyl]benzonitrile
Benzonitrile, 4-[(4-methyl-1-piperazinyl)methyl]-
4-((4-Methylpiperazin-1-yl)methyl)benzonitrile
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