p38α inhibitor 4
Modify Date: 2024-09-13 12:26:52
p38α inhibitor 4 structure
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Common Name | p38α inhibitor 4 | ||
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| CAS Number | 1262406-08-5 | Molecular Weight | 347.22 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H7F6N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of p38α inhibitor 4p38α inhibitor 4 (compound 10) is a selective and allosteric p38α inhibitor with an IC50 value of 1.2 μM. p38α inhibitor 4 exhibits no activity against p38β, p38γ, and p38δ[1]. |
| Name | 4-(Trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H- pyrazolo[3,4-b]pyridin-6-one |
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| Description | p38α inhibitor 4 (compound 10) is a selective and allosteric p38α inhibitor with an IC50 value of 1.2 μM. p38α inhibitor 4 exhibits no activity against p38β, p38γ, and p38δ[1]. |
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| Related Catalog | |
| Target |
p38α:1.2 μM (IC50) |
| References |
[1]. ACS Chem. Biol., Article ASAPDOI: 10.1021/cb1002619Publication Date (Web): November 23, 2010 |
| Molecular Formula | C14H7F6N3O |
|---|---|
| Molecular Weight | 347.22 |
| Exact Mass | 347.04900 |
| PSA | 61.80000 |
| LogP | 4.36810 |