Endo-BCN-Nitrobenzene

Modify Date: 2024-01-31 17:41:59

Endo-BCN-Nitrobenzene structure	Common Name	Endo-BCN-Nitrobenzene
	CAS Number	1263166-90-0	Molecular Weight	150.21800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₄O	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Endo-BCN-Nitrobenzene

Endo-BCN-Nitrobenzene is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	BCN alcohol
Synonym	More Synonyms

Description	Endo-BCN-Nitrobenzene is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

RIDADR	NONH for all modes of transport

Angew. Chem. Int. Ed. Engl. 49 , 9422-9425, (2010)

BCN

(1R,8S,9ξ)-bicyclo[6.1.0]non-4-yn-9-ylmethanol

(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-ylmethanol

BCN-OH

BCNM

(1R,8S,9s)-bicyclo[6.1.0]non-4-yne-9-ylmethanol

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