IKK2-IN-9

Modify Date: 2024-04-09 13:31:01

IKK2-IN-9 structure	Common Name	IKK2-IN-9
	CAS Number	1266240-89-4	Molecular Weight	394.497
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₂N₆OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IKK2-IN-9

IKK2-IN-9 is a potent, selective and orally active IKK2 inhibitor with IC50 of 19 nM, displays 20-fold selectivity over IKK1 (IC50=420 nM); inhibits lipopolysaccharide (LPS) induced TNFα production in human PBMCs with IC50 of 0.22 uM; dose-dependently inhibist the TNF-α response in murine model of acute inflammation.

Name	IKK2-IN-9

Description	IKK2-IN-9 is a potent, selective and orally active IKK2 inhibitor with IC50 of 19 nM, displays 20-fold selectivity over IKK1 (IC50=420 nM); inhibits lipopolysaccharide (LPS) induced TNFα production in human PBMCs with IC50 of 0.22 uM; dose-dependently inhibist the TNF-α response in murine model of acute inflammation.
References	References 1. Dyckman AJ, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):383-6. View Related Products by Target IκB kinase (IKK)

Molecular Formula	C₂₀H₂₂N₆OS
Molecular Weight	394.497

DC Chemicals Limited
China
Product Name: IKK2-IN-9
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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