1-Chloro-2-propanol

Modify Date: 2026-06-30 06:52:51

1-Chloro-2-propanol structure	Common Name	1-Chloro-2-propanol
	CAS Number	127-00-4	Molecular Weight	94.540
	Density	1.1±0.1 g/cm3	Boiling Point	126.5±0.0 °C at 760 mmHg
	Molecular Formula	C₃H₇ClO	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	54.5±15.3 °C
	Symbol	GHS02, GHS06	Signal Word	Danger

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	1-Chloro-2-propanol
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.1±0.1 g/cm3
Boiling Point	126.5±0.0 °C at 760 mmHg
Molecular Formula	C₃H₇ClO
Molecular Weight	94.540
Flash Point	54.5±15.3 °C
Exact Mass	94.018539
PSA	20.23000
LogP	0.27
Vapour Pressure	5.4±0.4 mmHg at 25°C
Index of Refraction	1.424
InChIKey	YYTSGNJTASLUOY-UHFFFAOYSA-N
SMILES	CC(O)CCl
Stability	Stable. Flammable. Incompatible with strong oxidizing agents.

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

1-Chloro-2-propanol MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA8942000

CHEMICAL NAME :: 2-Propanol, 1-chloro-

CAS REGISTRY NUMBER :: 127-00-4

BEILSTEIN REFERENCE NO. :: 0773653

LAST UPDATED :: 199712

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C3-H7-Cl-O

MOLECULAR WEIGHT :: 94.55

WISWESSER LINE NOTATION :: QY1&1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Insect - Drosophila melanogaster

DOSE/DURATION :: 1 ppb

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 23,51,1994

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS02, GHS06
Signal Word	Danger
Hazard Statements	H226-H301 + H331-H315-H319-H335
Precautionary Statements	Missing Phrase - N15.00950417-P210-P261-P304 + P340 + P312-P370 + P378-P403 + P233
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn: Harmful;
Risk Phrases	R10
Safety Phrases	26-36/39
RIDADR	UN 2611 6
WGK Germany	3
RTECS	UA8942000
Packaging Group	II
Hazard Class	6.1
HS Code	2905590090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:106-89-8 Epichlorohydrin CAS#:540-54-5 1-Chloropropane CAS#:75-56-9 epoxypropane CAS#:57-55-6 Propylene Glycol
CAS#:124-07-2 Octanoic acid CAS#:107-21-1 Ethylene glycol CAS#:78-95-5 Chloroacetone CAS#:67-56-1 Methanol
CAS#:627-30-5 3-Chloro-1-propanol CAS#:107-05-1 ALLYL CHLORIDE
DownStream 10
CAS#:4317-62-8 1-(3-METHYL-BEN... CAS#:37493-16-6 UNII:ZL0FUS96WW CAS#:42900-54-9 1-(4-Methoxyphe... CAS#:4402-32-8 1-(Diethylamino...
CAS#:4317-61-7 1-(2-Methylphen... CAS#:921-03-9 1,1,3-Trichloro... CAS#:18501-20-7 2-Propanol,1-hy... CAS#:57-55-6 Propylene Glycol
CAS#:25250-77-5 1-(butylamino)p... CAS#:2416-30-0 2-Propanol,1-[4...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2905590090
Summary	2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

NTP Toxicology and Carcinogenesis Studies of 1-Chloro-2-propanol (Technical Grade) (CAS NO. 127-00-4) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies.

Natl. Toxicol. Program Tech. Rep. Ser. 477 , 1-264, (1998)

1-Chloro-2-propanol and its positional isomer, 2-chloro-1-propanol, are used as chemical intermediates for the manufacture of propylene oxide, a starting material for production of polyurethane polyol...

Chemical mutagenesis testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program.

Environ. Mol. Mutagen. 23(1) , 51-63, (1994)

Fifty chemicals were tested for mutagenic activity in post-meiotic and meiotic germ cells of male Drosophila melanogaster using the sex-linked recessive lethal (SLRL) assay. As in the previous studies...

Haloperoxidases: Enzymatic Synthesis of alpha,beta-Halohydrins from Gaseous Alkenes.

Appl. Environ. Microbiol. 45(2) , 366-74, (1983)

The enzymatic synthesis of alpha,beta-halohydrins from gaseous alkenes is described. The enzymatic reaction required an alkene, a halide ion, dilute hydrogen peroxide, and a haloperoxidase enzyme. A w...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01

Name: Adrenergic beta2 receptor (ADRB2) small molecule agonists, cell-based qHTS assay
Source: 824
External Id: ADRB2293

Total 210, Current Page 1 of 21

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

.α.-Propylene chlorohydrin

sec-Propylene Chlorohydrin

EINECS 204-819-6

1-Chloro-2-propanol

Chloropropanol,Propylene chlorohydrin

Propylene chlorohydrin

UNII:ZL0FUS96WW

MFCD00004530

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of 1-Chloro-2-propanol?

A: CAS number of 1-Chloro-2-propanol is 127-00-4.

Q: What is the English name of 1-Chloro-2-propanol?

A: The English name of 1-Chloro-2-propanol is 1-Chloro-2-propanol.

Q: What is the boiling point of 1-Chloro-2-propanol?

A: Boiling point of 1-Chloro-2-propanol is 126.5±0.0 °C at 760 mmHg.

Q: What is the InChIKey of 1-Chloro-2-propanol?

A: InChIKey of 1-Chloro-2-propanol is YYTSGNJTASLUOY-UHFFFAOYSA-N.

Q: What is the LogP of 1-Chloro-2-propanol?

A: LogP of 1-Chloro-2-propanol is 0.27.

Q: What is the molecular formula of 1-Chloro-2-propanol?

A: Molecular formula of 1-Chloro-2-propanol is C3H7ClO.

Q: What is the polar surface area (PSA) of 1-Chloro-2-propanol?

A: Polar surface area (PSA) of 1-Chloro-2-propanol is 20.23000.

Q: What is the SMILES notation of 1-Chloro-2-propanol?

A: SMILES notation of 1-Chloro-2-propanol is CC(O)CCl.

Q: What is the molecular weight of 1-Chloro-2-propanol?

A: Molecular weight of 1-Chloro-2-propanol is 94.540.

Q: What are the upstream materials of 1-Chloro-2-propanol?

A: Related upstream materials(CAS) of 1-Chloro-2-propanol: 106-89-8;540-54-5;75-56-9;57-55-6;124-07-2;107-21-1;78-95-5;67-56-1;627-30-5;107-05-1.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-Chloro-2-propanol
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-Chloro-2-propanol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 1-Chloro-2-propanol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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1-Chloro-2-propanol

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MSDS

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.