Basifungin

Modify Date: 2024-01-09 18:18:37

Basifungin Structure
Basifungin structure
Common Name Basifungin
CAS Number 127785-64-2 Molecular Weight 1101.42000
Density 1.19g/cm3 Boiling Point 1229.1ºC at 760 mmHg
Molecular Formula C60H92N8O11 Melting Point N/A
MSDS N/A Flash Point 697.1ºC

 Use of Basifungin


Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A (Basifungin) A is an inhibitor of the inositolphosphorylceramide synthase AUR1[1][2].

 Names

Name aureobasidin A
Synonym More Synonyms

 Basifungin Biological Activity

Description Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A (Basifungin) A is an inhibitor of the inositolphosphorylceramide synthase AUR1[1][2].
Related Catalog
In Vitro Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides[2].
References

[1]. K Ikai, et al. Structure of aureobasidin A. J Antibiot (Tokyo). 1991 Sep;44(9):925-33.

[2]. Vanessa Cerantola, et al. Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides. Mol Microbiol. 2009 Mar;71(6):1523-37.

[3]. K Kino, et al. Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins. FEBS Lett. 1996 Dec 9;399(1-2):29-32.

 Chemical & Physical Properties

Density 1.19g/cm3
Boiling Point 1229.1ºC at 760 mmHg
Molecular Formula C60H92N8O11
Molecular Weight 1101.42000
Flash Point 697.1ºC
Exact Mass 1100.69000
PSA 245.85000
LogP 4.88900
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.574

 Synonyms

aurantoside B
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