t-boc-N-amido-PEG6-azide

Modify Date: 2024-01-10 19:17:36

t-boc-N-amido-PEG6-azide Structure
t-boc-N-amido-PEG6-azide structure
Common Name t-boc-N-amido-PEG6-azide
CAS Number 1292268-15-5 Molecular Weight 450.53
Density N/A Boiling Point N/A
Molecular Formula C19H38N4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-boc-N-amido-PEG6-azide


Boc-NH-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-NH-PEG6-azide

 t-boc-N-amido-PEG6-azide Biological Activity

Description Boc-NH-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H38N4O8
Molecular Weight 450.53