Azido-PEG3-SS-PEG3-azide

Modify Date: 2024-01-08 23:23:20

Azido-PEG3-SS-PEG3-azide Structure
Azido-PEG3-SS-PEG3-azide structure
Common Name Azido-PEG3-SS-PEG3-azide
CAS Number 1310827-27-0 Molecular Weight 468.592
Density N/A Boiling Point N/A
Molecular Formula C16H32N6O6S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-SS-PEG3-azide


Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-SS-PEG3-azide
Synonym More Synonyms

 Azido-PEG3-SS-PEG3-azide Biological Activity

Description Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H32N6O6S2
Molecular Weight 468.592
Exact Mass 468.182465
LogP 0.93

 Synonyms

MFCD28976667
3,6,9,16,19,22-Hexaoxa-12,13-dithiatetracosane, 1,24-diazido-
1,24-Diazido-3,6,9,16,19,22-hexaoxa-12,13-dithiatetracosane