- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Amino-PEG3-C2-Azido
- Price: Check
- Purity: 97.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Amino-PEG3-C2-Azido
- Price: ￥1650.0/1g ￥5230.0/5g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: Amino-PEG3-C2-Azido
- Price: ￥Inquiry/10g
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- Email: sales@pu-kang.com
- DC Chemicals Limited
- China
- Product Name: Azido-PEG3-amine
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Shanghai Amole Biotechnology Co., Ltd.
- China
- Product Name: Amino-PEG3-C2-Azido
- Price: ￥Inquiry/1g ￥Inquiry/200mg ￥Inquiry/5g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Xiyao Wang
- Email: 3623107365@qq.com
134179-38-7
134179-38-7 structure
- Name: Amino-PEG3-C2-Azido
- Chemical Name: 11-Azido-3,6,9-trioxaundecan-1-amine
- CAS Number: 134179-38-7
- Molecular Formula: C8H18N4O3
- Molecular Weight: 218.25400
- Catalog: Chemical reagent Organic reagent Azide
- Create Date: 2018-12-28 17:23:13
- Modify Date: 2025-08-21 17:18:04
-
Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645)[1].
| Name | 11-Azido-3,6,9-trioxaundecan-1-amine |
|---|---|
| Synonyms |
Azido-PEG3-Amine
Amino-PEG3-Azide 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanamine 1-Amino-11-azido-3,6,9-trioxaundecane 11-Amino-3,6,9-trioxaundecanyl Azide |
| Description | Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Pomalidomide (a CRBN ligand and a known immunomodulatory imide drug (IMiD)) is conjugated to Rucaparib through a tri(ethylene glycol) (PEG3) linker to afford a compound that we designate as iRucaparib-TP3 (IMiD-Rucaparib with a triazole-PEG3 linker). iRucaparib-TP3 induces PARP1 degradation[1]. |
| References |
| Density | 1.1 |
|---|---|
| Boiling Point | 198-202ºC |
| Molecular Formula | C8H18N4O3 |
| Molecular Weight | 218.25400 |
| Exact Mass | 218.13800 |
| PSA | 103.46000 |
| LogP | 0.45826 |
| Index of Refraction | 1.47 |
| Storage condition | Amber Vial, Refrigerator, Under Inert Atmosphere |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C,Xi |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2735 |
| WGK Germany | 3 |
| Packaging Group | III |
| HS Code | 2929909090 |
| Precursor 7 | |
|---|---|
| DownStream 3 | |
![methanesulfonic acid 2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl ester structure](https://image.chemsrc.com/caspic/438/134179-43-4.png)
![1-azido-11-[(tert-butyldimethylsilyl)oxy]-3,6,9-trioxaundecane structure](https://image.chemsrc.com/caspic/476/134179-42-3.png)
![2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetic acid structure](https://image.chemsrc.com/caspic/086/239081-53-9.png)
| HS Code | 2929909090 |
|---|---|
| Summary | 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |