Azido-PEG3-succinimidyl carbonate

Modify Date: 2024-01-08 03:32:17

Azido-PEG3-succinimidyl carbonate Structure
Azido-PEG3-succinimidyl carbonate structure
Common Name Azido-PEG3-succinimidyl carbonate
CAS Number 2110448-98-9 Molecular Weight 360.32
Density N/A Boiling Point N/A
Molecular Formula C13H20N4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-succinimidyl carbonate


Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-O-NHS ester

 Azido-PEG3-succinimidyl carbonate Biological Activity

Description Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H20N4O8
Molecular Weight 360.32