DNQX disodium salt
Modify Date: 2024-01-10 10:27:13
DNQX disodium salt structure
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Common Name | DNQX disodium salt | ||
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| CAS Number | 1312992-24-7 | Molecular Weight | 296.104 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H2N4Na2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DNQX disodium saltDNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively)[1]. |
| Name | DNQX disodium salt |
|---|---|
| Synonym | More Synonyms |
| Description | DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively)[1]. |
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| Related Catalog | |
| Target |
Non-NMDA Receptor[1] |
| In Vitro | DNQX (FG 9041) disodium salt selectively depolarizes thalamic reticular nucleus (TRN) neurons[2]. |
| In Vivo | DNQX (FG 9041), a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex[3]. |
| References |
| Molecular Formula | C8H2N4Na2O6 |
|---|---|
| Molecular Weight | 296.104 |
| Exact Mass | 295.976959 |
| 2,3-Quinoxalinedione, 1,4-dihydro-6,7-dinitro-, sodium salt (1:2) |
| Disodium 6,7-dinitro-2,3-quinoxalinediolate |
| Disodium 6,7-dinitroquinoxaline-2,3-diolate |