Polatuzumab vedotin
Modify Date: 2024-01-17 14:21:29
Polatuzumab vedotin structure
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Common Name | Polatuzumab vedotin | ||
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| CAS Number | 1313206-42-6 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Polatuzumab vedotinPolatuzumab vedotin is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. Polatuzumab vedotin has the potential for the research of Large B-cell lymphomas (LBCL)[1]. |
| Name | Polatuzumab vedotin |
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| Description | Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. Polatuzumab vedotin has the potential for the research of Large B-cell lymphomas (LBCL)[1]. |
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| Related Catalog | |
| In Vivo | Polatuzumab vedotin (0.3, 1, 3, 6, 12 mg/kg; i.v.; once) shows anti-tumor in a mouse tumour xenograft model of human diffuse large B‐cell lymphoma WSU‐DLCL2[2]. Animal Model: SCID mice (human diffuse large B-cell lymphoma WSU-DLCL2)[2] Dosage: 0.3, 1, 3, 6, 12 mg/kg Administration: I.v.; once Result: Showed dose-dependent tumour growth inhibition. |
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| No Any Chemical & Physical Properties |