Pheniramine maleate

Modify Date: 2024-01-02 16:27:08

Pheniramine maleate structure	Common Name	Pheniramine maleate
	CAS Number	132-20-7	Molecular Weight	356.416
	Density	N/A	Boiling Point	348.3ºC at 760 mmHg
	Molecular Formula	C₂₀H₂₄N₂O₄	Melting Point	104-108°C
	MSDS	Chinese USA	Flash Point	164.5ºC
	Symbol	GHS07	Signal Word	Warning

Use of Pheniramine maleate

Pheniramine Maleate ia an antihistamine and vasoconstrictor.

Name	Pheniramine Maleate
Synonym	More Synonyms

Description	Pheniramine Maleate ia an antihistamine and vasoconstrictor.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology

Boiling Point	348.3ºC at 760 mmHg
Melting Point	104-108°C
Molecular Formula	C₂₀H₂₄N₂O₄
Molecular Weight	356.416
Flash Point	164.5ºC
Exact Mass	356.173615
PSA	90.73000
LogP	2.87700
Vapour Pressure	5.07E-05mmHg at 25°C
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	>=1 g/100 mL at 24 ºC

Pheniramine maleate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT0175000

CAS REGISTRY NUMBER :: 132-20-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C16-H20-N2.C4-H4-O4

MOLECULAR WEIGHT :: 356.46

WISWESSER LINE NOTATION :: T6NJ BYR&2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - antipsychotic Lungs, Thorax, or Respiration - cyanosis

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 520 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - changes in motor activity (specific assay) Behavioral - aggression

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 268 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - changes in motor activity (specific assay) Behavioral - aggression

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 111 mg/kg

TOXIC EFFECTS :: Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 270 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 72 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 1120 ug/kg

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 19,516,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83158 No. of Facilities: 1580 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 6126 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83158 No. of Facilities: 12 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 494 (estimated) No. of Female Employees: 206 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UT0175000

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(2Z)-But-2-endisäure--N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amin(1:1)

Pheniramine maleate

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EINECS 205-051-4

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N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine (2Z)-but-2-enedioate

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Pheniramine maleate salt

2-Pyridinepropanamine, N,N-dimethyl-γ-phenyl-, (2Z)-2-butenedioate (1:1)

N,N-Dimethyl-3-phenyl-3-(2-pyridinyl)-1-propanamine (2Z)-2-butenedioate (1:1)

acide (2Z)-but-2-ènedioïque - N,N-diméthyl-3-phényl-3-pyridin-2-ylpropan-1-amine (1:1)

UNII:NYW905655B

Naphcon A

MFCD00079250

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pheniramine maleate
Price: ￥1218.0/5g ￥438.0/1g
Purity: 99.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Pheniramine Maleate
Price: $300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pheniramine maleate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: PHENIRAMINE MALEATE
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: $66/10mM*1mLinWater

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