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132-20-7

132-20-7 structure
132-20-7 structure
  • Name: Pheniramine maleate
  • Chemical Name: Pheniramine Maleate
  • CAS Number: 132-20-7
  • Molecular Formula: C20H24N2O4
  • Molecular Weight: 356.416
  • Catalog: API Antiallergic Antihistamine
  • Create Date: 2018-08-31 15:42:30
  • Modify Date: 2025-08-20 15:00:47
  • Pheniramine Maleate ia an antihistamine and vasoconstrictor.
Name Pheniramine Maleate
Synonyms (2Z)-But-2-endisäure--N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amin(1:1)
Pheniramine maleate
1-(N,N-Dimethylamino)-3-(phenyl-3-a-pyridyl)propane Maleate
N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine (2Z)-but-2-enedioate (1:1)
EINECS 205-051-4
3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylamine Maleate
N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine (2Z)-but-2-enedioate
(Z)-but-2-enedioic acid,N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine
Pheniramine maleate salt
2-Pyridinepropanamine, N,N-dimethyl-γ-phenyl-, (2Z)-2-butenedioate (1:1)
N,N-Dimethyl-3-phenyl-3-(2-pyridinyl)-1-propanamine (2Z)-2-butenedioate (1:1)
acide (2Z)-but-2-ènedioïque - N,N-diméthyl-3-phényl-3-pyridin-2-ylpropan-1-amine (1:1)
UNII:NYW905655B
Naphcon A
MFCD00079250
Description Pheniramine Maleate ia an antihistamine and vasoconstrictor.
Related Catalog
Boiling Point 348.3ºC at 760 mmHg
Melting Point 104-108°C
Molecular Formula C20H24N2O4
Molecular Weight 356.416
Flash Point 164.5ºC
Exact Mass 356.173615
PSA 90.73000
LogP 2.87700
Vapour Pressure 5.07E-05mmHg at 25°C
Stability Stable. Incompatible with strong oxidizing agents.
Water Solubility >=1 g/100 mL at 24 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT0175000
CAS REGISTRY NUMBER :
132-20-7
LAST UPDATED :
199701
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C16-H20-N2.C4-H4-O4
MOLECULAR WEIGHT :
356.46
WISWESSER LINE NOTATION :
T6NJ BYR&2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - antipsychotic Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
520 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - changes in motor activity (specific assay) Behavioral - aggression
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
268 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - changes in motor activity (specific assay) Behavioral - aggression
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
111 mg/kg
TOXIC EFFECTS :
Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
270 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
72 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
1120 ug/kg
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 19,516,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83158 No. of Facilities: 1580 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 6126 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83158 No. of Facilities: 12 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 494 (estimated) No. of Female Employees: 206 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UT0175000
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