![]() Chlorpheniramine structure
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Common Name | Chlorpheniramine | ||
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CAS Number | 132-22-9 | Molecular Weight | 274.78800 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C16H19ClN2 | Melting Point | 25 °C (lit.) | |
MSDS | N/A | Flash Point | N/A |
Use of ChlorpheniramineChlorpheniramine is a H1 antihistamines commonly used in allergic diseases[1]. [2]. . |
Name | chlorphenamine |
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Synonym | More Synonyms |
Description | Chlorpheniramine is a H1 antihistamines commonly used in allergic diseases[1]. [2]. . |
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Related Catalog | |
Target |
IC50: 43μM in BV2 microglial cells |
In Vitro | Chlorpheniramine has an inhibitory effects with an value of IC50 is 43μM on proton currents in BV2 microglial cells[1]. . Cell Viability Assay Cell Line: Murine microglial BV2 cells[1]. Concentration: 100 μM Incubation Time: 5 min Result: Inhibited proton currents with moderate potency. |
In Vivo | Chloropheniramine (50, 100 and 200 μg/kg; IM; 3 times, at intervals of 1 week) enhances white blood cells in the peripheral blood[2]. . Animal Model: Sprague-Dawley (SD) rats[2]. Dosage: 50, 100 and 200 μg/kg Administration: Chlorpheniramine (50, 100 and 200 μg/kg; IM; 3 times, at intervals of 1 week) Result: Enhanced white blood cells in the peripheral blood, mostly due to the increases of B cells and monocytes, but not T cells and NK cells. |
References |
Melting Point | 25 °C (lit.) |
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Molecular Formula | C16H19ClN2 |
Molecular Weight | 274.78800 |
Exact Mass | 274.12400 |
PSA | 16.13000 |
LogP | 3.81860 |
Precursor 8 | |
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DownStream 3 | |
(S)-[3-(4-chloro-phenyl)-3-[2]pyridyl-propyl]-dimethyl-amine |
D-Chlorpheniramine |
Isomerine |
Phendextro |
Dexclorfeniramina |
Polaramin |
Chlor-Trimeton |
Fortamine |
(+)-Chlorpheniramine |
DEXCHLORPHENIRAMINE |
[3H]-Chlorpheniramine |
chloropheniramine |
3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine |
Destral |
(S)-[3-(4-Chlor-phenyl)-3-[2]pyridyl-propyl]-dimethyl-amin |
Trenelone |