Dexchlorpheniramine

Modify Date: 2024-01-09 18:19:03

Dexchlorpheniramine Structure
Dexchlorpheniramine structure
Common Name Dexchlorpheniramine
CAS Number 25523-97-1 Molecular Weight 274.78800
Density 1.107g/cm3 Boiling Point 379ºC at 760mmHg
Molecular Formula C16H19ClN2 Melting Point N/A
MSDS N/A Flash Point 183ºC

 Use of Dexchlorpheniramine


Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies[1].

 Names

Name dexchlorpheniramine
Synonym More Synonyms

 Dexchlorpheniramine Biological Activity

Description Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies[1].
Related Catalog
In Vivo Dexchlorpheniramine (2-10 mg/kg; IP, single dosage) and Ranitidine (10-50 mg/kg) co-administration can Simultaneous blockade of H1 and H2 receptors, and protects both the cortical plate and the white matter against the excitotoxic challenge in Swiss pups pretreated with IL-9[1].
References

[1]. Patkai J, et al. Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain. Pediatr Res. 2001 Aug;50(2):222-30.

 Chemical & Physical Properties

Density 1.107g/cm3
Boiling Point 379ºC at 760mmHg
Molecular Formula C16H19ClN2
Molecular Weight 274.78800
Flash Point 183ºC
Exact Mass 274.12400
PSA 16.13000
LogP 3.81860
Index of Refraction 1.565

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

Phendextro
(3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
D-Chlorpheniramine
dexchlorphenamine
Isomerine
Dexclorfeniramina
Fortamine
Trenelone
Polaramin
DEXCHLORPHENIRAMINE
Destral
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