(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy

Modify Date: 2024-01-10 10:58:20

(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure
(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy structure
Common Name (2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy
CAS Number 132622-69-6 Molecular Weight 230.261
Density 1.2±0.1 g/cm3 Boiling Point 371.1±42.0 °C at 760 mmHg
Molecular Formula C10H18N2O4 Melting Point N/A
MSDS N/A Flash Point 178.2±27.9 °C

 Names

Name (2S,4R)-1-Boc-4-aminopyrrolidine-2-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 371.1±42.0 °C at 760 mmHg
Molecular Formula C10H18N2O4
Molecular Weight 230.261
Flash Point 178.2±27.9 °C
Exact Mass 230.126663
PSA 92.86000
LogP -0.36
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.517

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36

 Synthetic Route

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(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: US2008/107623 A1, ; Page/Page column 75-76 ;

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(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: Fisher, Abigail; Mann, Amandeep; Verma, Vaneeta; Thomas, Nancy; Mishra, Ram K.; Johnson, Rodney L. Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 307 - 317

~65%

(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: Webb, Thomas R.; Eigenbrot, Charles Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3009 - 3016

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(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: Journal of Medicinal Chemistry, , vol. 49, # 1 p. 307 - 317

~%

(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: Journal of Medicinal Chemistry, , vol. 49, # 1 p. 307 - 317

~%

(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: Journal of Organic Chemistry, , vol. 56, # 9 p. 3009 - 3016

~%

(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: Journal of Organic Chemistry, , vol. 56, # 9 p. 3009 - 3016

~%

(2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxy Structure

(2S,4R)-4-amino...

CAS#:132622-69-6

Literature: Journal of Organic Chemistry, , vol. 56, # 9 p. 3009 - 3016

 Synonyms

(4R)-4-amino-1-(tert-butoxycarbonyl)-L-proline
(2S,4R)-4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
1,2-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) ester, (2S,4R)-
(4R)-4-Amino-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
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