Bis-propargyl-PEG11

Modify Date: 2024-01-10 13:45:37

Bis-propargyl-PEG11 Structure
Bis-propargyl-PEG11 structure
Common Name Bis-propargyl-PEG11
CAS Number 1351373-48-2 Molecular Weight 534.64
Density N/A Boiling Point N/A
Molecular Formula C26H46O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-propargyl-PEG11


Bis-propargyl-PEG10 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-propargyl-PEG10

 Bis-propargyl-PEG11 Biological Activity

Description Bis-propargyl-PEG10 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H46O11
Molecular Weight 534.64