GWJ-A-23 structure
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Common Name | GWJ-A-23 | ||
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CAS Number | 1351930-95-4 | Molecular Weight | 385.346 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C17H28NO4P | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of GWJ-A-23GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo. |
Name | Disodium [4-(decanoylamino)benzyl]phosphonate |
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Synonym | More Synonyms |
Description | GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo. |
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References | References 1. Jiang G, et al. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5098-101. View Related Products by Target Autotaxin |
Molecular Formula | C17H28NO4P |
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Molecular Weight | 385.346 |
Exact Mass | 385.139496 |
Phosphonic acid, [[4-[(1-oxodecyl)amino]phenyl]methyl]-, sodium salt (1:2) |
Disodium [4-(decanoylamino)benzyl]phosphonate |