Azido-PEG5-S-methyl ethanethioate

Modify Date: 2024-01-12 12:09:06

Azido-PEG5-S-methyl ethanethioate Structure
Azido-PEG5-S-methyl ethanethioate structure
Common Name Azido-PEG5-S-methyl ethanethioate
CAS Number 1352221-64-7 Molecular Weight 365.45
Density N/A Boiling Point N/A
Molecular Formula C14H27N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG5-S-methyl ethanethioate


Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG5-S-methyl ethanethioate

 Azido-PEG5-S-methyl ethanethioate Biological Activity

Description Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H27N3O6S
Molecular Weight 365.45